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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Eugenol
supplement:
Glutathione
Research Papers that Mention the Interaction
“ EU treatment caused enhanced activities of enzymic antioxidants and diminished both GSH and total thiols.”
“Further EU enhanced the reduced glutathione ( GSH ) levels and also ameliorated the levels of 3 - nitrotyrosine and expression of HSP70.”
Neurorestorative effects of eugenol, a spice bioactive: Evidence in cell model and its efficacy as an intervention molecule to abrogate brain oxidative dysfunctions in the streptozotocin diabetic rat“At concentrations of 3 mmol/L and 4 mmol/L, eugenol depleted about 45% and 77% of GSH after one-hour incubation.”
“Additionally, eugenol treatment significantly restored the decreased serum levels of insulin and glutathione when compared to that of the diabetic control rats.”
Eugenol ameliorates insulin resistance, oxidative stress and inflammation in high fat‐diet/streptozotocin‐induced diabetic rat“Concentrations of 1 mM eugenol caused a loss of over 90% of intracellular glutathione and resulted in approximately 85% cell death over a 5-h incubation period.”
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