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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Etorphine and Yohimbine

supplement:

Yohimbine

Research Papers that Mention the Interaction

Yohimbine did not suppress the inhibitory effect of etorphine on protein output but showed some antagonism against the effects of etorphine on water and bicarbonate output.
European journal of pharmacology  •  1986  |  View Paper
Conversely, systemic yohimbine (1 mg/kg) attenuated the effects of central etorphine , and diminished potentiation of etorphine by the alpha 2 agonists.
Prior microinjection of clonidine (5 micrograms) or guanfacine (5 micrograms) into the locus coeruleus (LC) reduced the intensity of central etorphine antinociception whereas central yohimbine (20 micrograms) pretreatment increased peak antinociceptive activity and prolonged the duration of etorphine.
Brain research  •  1984  |  View Paper