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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Etorphine and Sodium Bicarbonate

Research Papers that Mention the Interaction

The combination of large doses of sodium bicarbonate and the potent narcotic, etorphine , has reportedly been given to racehorses in attempts to improve their performance and also to "mask" the presence of etorphine in urine samples.
The increased urinary output and pH associated with sodium bicarbonate (approximately 500 g) administration may reduce the urinary concentration of etorphine , making it more difficult to detect.
We conclude that the coadministration of etorphine and sodium bicarbonate or sodium chloride can make the detection of etorphine more difficult because of the dilutional effects associated with the administration of a large electrolyte load.
Journal of analytical toxicology  •  1996  |  View Paper