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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“SummaryA significant myeloprotective effect of melatonin in mice treated with etoposide , cyclophosphamide or carboplatin has been reported.”
Double-blind randomized study on the myeloprotective effect of melatonin in combination with carboplatin and etoposide in advanced lung cancer“ Melatonin reduced the effects of etoposide significantly in both types of experiment conditions, through the reduction of the level of DNA damage measured via comet assay.”
“The most protective effect was observed with melatonin when it was administrated 24 h before etoposide treatment.”
“In addition to cytokines such as hrTNF‐alpha and TRAIL, chemotherapeutic compounds, including doxorubicin, docetaxel, or etoposide , were employed in combination with melatonin to promote cell death.”
“In vitro, melatonin proved to counteract apoptosis in bone marrow cells incubated with etoposide.”
Hematopoietic rescue via T-cell-dependent, endogenous granulocyte-macrophage colony-stimulating factor induced by the pineal neurohormone melatonin in tumor-bearing mice.“Animal models further demonstrated that a combination of melatonin and the chemotherapeutic agent etoposide (VP16) can significantly enhance tumor growth inhibition compared with monotherapy.”
Melatonin Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Through Long Non-Coding RNA RAD51-AS1-Mediated Suppression of DNA Repair
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