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Discover Supplement-Drug Interactions

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Possible Interaction: Etomidate and Vitamin C


Vitamin C

Research Papers that Mention the Interaction

Since the generation of steroids requires reductive and energy rich equivalents, the present study examined whether supplementation with ascorbic acid or xylitol, a major source of NADPH, could attenuate adrenal suppression by etomidate in human subjects by promoting the turnover rate of 11-beta-hydroxylase.
European journal of anaesthesiology  •  1996  |  View Paper
This study was carried out to assess whether the adrenal inhibition induced by etomidate could be prevented by associating ascorbic acid with etomidate, as a protective effect of ascorbic acid administered three hours after etomidate has been described.
Annales francaises d'anesthesie et de reanimation  •  1991  |  View Paper
Serious side-effects of etomidate have only been observed in guinea-pigs and in man, both species relying for … ascorbic acid pools upon resynthesis and upon the daily dietary intake of vitamin C. It has been shown that ascorbic acid and not ACTH can … serum cortisol concentration during etomidate ….
European journal of anaesthesiology  •  1986  |  View Paper