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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Etomidate
supplement:
Progesterone
Research Papers that Mention the Interaction
“Finally, the concentration of progesterone was strongly enhanced with high doses of miconazole, whereas etomidate suppressed progesterone production.”
Differential effects of the imidazole derivatives etomidate, ketoconazole and miconazole and of metyrapone on the secretion of cortisol and its precursors by human adrenocortical cells.“17-alpha-OH-progesterone and progesterone were found diminished at etomidate plasma levels greater than 1.0 micrograms/ml.”
“At higher concentrations (greater than 10(-6) M), etomidate also inhibited ovarian oestradiol production, testicular androgen formation and ovarian progesterone synthesis.”
Comparative effects of etomidate and its fluoro analogue, R 8110 on testicular, adrenal and ovarian steroid biosynthesis.“ Etomidate , an anaesthetic drug known to interfere with adrenal steroid synthesis, blocks not only corticosterone but also aldosterone and, to a lesser degree, progesterone release.”
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