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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Etomidate
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“ Etomidate (5 × 10-5 M) significantly attenuated the contractile response induced by the addition of calcium in the calcium-free isotonic depolarizing solution.”
Etomidate attenuates phenylephrine-induced contraction in isolated rat aorta“When extracellular albumin concentration was kept constant (20 g/L), increasing the concentration of etomidate by one log restored its inhibitory effect on the calcium signal.”
“ConclusionsThese findings indicate that the direct negative Inotropic effect of etomidate results from a decrease in intracellular Ca++ availability with no changes in myofibrillar Ca++ sensitivity.”
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