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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Etomidate and Calcium Supplement

Research Papers that Mention the Interaction

Etomidate (5 × 10-5 M) significantly attenuated the contractile response induced by the addition of calcium in the calcium-free isotonic depolarizing solution.
Canadian journal of anaesthesia = Journal canadien d'anesthesie  •  2005  |  View Paper
Etomidate alters the Ca++ mobilization elicited by Ang II in rat aortic VSMC, suggesting that the vascular response to Ang II may be altered during etomidate anesthesia.
Journal of cardiovascular pharmacology  •  2004  |  View Paper
When extracellular albumin concentration was kept constant (20 g/L), increasing the concentration of etomidate by one log restored its inhibitory effect on the calcium signal.
Fundamental & clinical pharmacology  •  2000  |  View Paper
CONCLUSIONS These findings indicate that the direct negative inotropic effect of etomidate results from a decrease in intracellular Ca++ availability with no changes in myofibrillar Ca++ sensitivity.
CONCLUSIONS These findings indicate that the direct negative inotropic effect of etomidate results from a decrease in intracellular Ca++ availability with no changes in myofibrillar Ca++ sensitivity.
Anesthesiology  •  1993  |  View Paper
At 0.5 mM Ca++ 5 micrograms/ml etomidate increased Vmax (128 +/- 18%, P less than 0.05) but not force (103 +/- 16%, NS).
Anesthesiology  •  1990  |  View Paper