“Commonly used anticonvulsants such as voltage-gated Na+ channel blockers, phenytoin and carbamazepine, and voltage-gated Ca2+ channel blockers, gabapentin and ethosuximide , induced dose-dependent analgesia in the injected paw , with ED50 values of 0.30, 0.32 and 8, 410 microg per 100 microl, respectively.”