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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ethinyl Estradiol
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“ Ethinyl estradiol gradually decreases plasma and urinary calcium and phosphate levels reaching a maximum at about 6 months.”
Effects of oestrogen and progestogen therapy on calcium metabolism in post-menopausal women.“ Ethinyl estradiol and estradiol-17β also inhibited Ca uptake but the inhibition was smaller than DES and in the order DES > ethinyl estradiol > estradiol-17β.”
“It is concluded that ethinyloestradiol produces an improvement in calcium and phosphorus balance and a decrease in plasma calcium and phosphorus in primary hyperparathyroidism by decreasing bone resorption.”
“Relaxation to 17alpha-estradiol was not inhibited by propranolol, tamoxifen, ICI 182,780, cycloheximide … D. The KCl contractions were also sensitive to 17alpha-estradiol-induced relaxation and calcium contractions in depolarized tissues … markedly prevented by 17alpha-estradiol , implying a reduction of extracellular calcium … through voltage-operated calcium channels (VOCCs).”
Evidence that 17alpha-estradiol is biologically active in the uterine tissue: Antiuterotonic and antiuterotrophic action
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