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Last Updated: 3 years ago

Possible Interaction: Ethanol and Urokinase-Type Plasminogen Activator

Research Papers that Mention the Interaction

Ethanol and in a greater degree acetaldehyde inhibit activation of plasminogen evoked by urokinase and streptokinase.
Roczniki Akademii Medycznej w Bialymstoku = Annales Academiae Medicae Bialostocensis  •  1988  |  View Paper
Taken together, our results are the first to implicate uPA inhibition in the regulation of ethanol consumption and preference, and suggest that uPA may be considered as a possible therapeutic drug target for alcoholism and abstinence.
Drug design, development and therapy  •  2014  |  View Paper
In addition, wounds from mice exposed to ethanol had significantly increased levels of active urokinase plasminogen activator at day 7, (205.10 +/- 48.79 vs 642.70 +/- 159.80 pg/microg protein, p<0.001).
Alcoholism, clinical and experimental research  •  2007  |  View Paper
The alcohol n‐butanol , a phospholipase D and protein kinase C inhibitor, besides inhibiting constitutive uPA secretion, blocked staurosporine‐induced secretion.
International journal of cancer  •  1998  |  View Paper