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Last Updated: 2 years ago

Possible Interaction: Ethanol and Ubiquinone





Research Papers that Mention the Interaction

Moreover, two different female patients (cases 2 and 10) who once had palpitations when they consumed alcohol noticed the disappearance of the symptom after taking coenzyme Q10 , which has a therapeutic effect on mitochondrial abnormality (3).
Diabetes Care  •  1995  |  View Paper
Conclusion: CoQ10 rescues apoptotic response through caspase-2 inhibition toward EtOH treatment.
The Journal of Biological Chemistry  •  2013  |  View Paper
Ethanol , either separately or in combination with lovastatin, diminished liver stores of CoQ10 by almost 40%.
Molecular aspects of medicine  •  1994  |  View Paper
ethanol … quinone derivatives 2,3-dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone (ubidecarenone, coenzyme Q10), 4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-… to ethanol load, at a dose of 10, 11.5 and 30 mg/kg of body weight, respectively.
Pharmacology  •  1988  |  View Paper
In vivo modulation of ubiquinone with ethanol and in vitro pentane extraction show that ubiquinone is not required either for NADH‐ferricyanide reductase, acetaldehyde dehydrogenase activity, or Ca2+ and Mg2+ stimulated ATPases.
Cell biochemistry and function  •  1986  |  View Paper
CoQ10 could antagonize the apoptosis inducing effect of EtOH.
In EtOH-exposed corneal fibroblasts, CoQ10 pretreatment significantly reduced mitochondrial depolarization and ROS production at 30, 60, 90, and 120 min and inhibited the activation and expression of caspases 2 and 3 at 2 h after EtOH exposure.
The inhibition of cell apoptosis by CoQ10 was significant at 8 and 12 h after EtOH exposure.
These findings support the proposition that CoQ10 plays an antiapoptotic role in corneal fibroblasts after ethanol exposure.
PloS one  •  2011  |  View Paper