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Last Updated: 2 years ago

Possible Interaction: Ethanol and Triazolam

supplement:

Ethanol

Research Papers that Mention the Interaction

Prior to receiving triazolam , as with all hypnotic agents, patients should be cautioned about the additive effects of other depressant drugs and alcohol , and the possibility of residual effects on performance the morning after ingestion.
Drugs  •  2012  |  View Paper
The findings of the present study … that even a moderate amount of ethanol in combination with … clinical dose of triazolam or temazepam can cause performance impairment that might diminish an individual's ability to respond … to unexpected demands (e.g. smoke alarms or middle-of-the-night child care).
Journal of psychopharmacology  •  2002  |  View Paper
Among the participants who reported any sedative-like responses to ethanol, the sedative-like effects of ethanol and triazolam were positively correlated.
That is, subjects who exhibited the steepest dose-related effects on measures of subjective sedation after ethanol also exhibited the steepest slopes after triazolam.
Behavioural pharmacology  •  1999  |  View Paper
Thus, triazolam produced response rate slowing at relatively lower doses than ethanol.
Drug and alcohol dependence  •  1993  |  View Paper
After ethanol, triazolam total AUC0‐∞. increased (X̄ ± SD = 21% ± 18%).
Clinical pharmacology and therapeutics  •  1985  |  View Paper
The potential pharmacodynamic interaction of triazolam and ethanol is more important than the minimal pharmacokinetic interaction.
Journal of clinical psychopharmacology  •  1984  |  View Paper
Toxic levels may be reached by simultaneous administration of ethanol and triazolam.
Journal of clinical forensic medicine  •  2005  |  View Paper
Ethanol inhibited metabolism of nifedipine (oxidized nifedipine IC50 3 mg dL−1, where … inhibitor concentration corresponding to a 50% reduction in metabolite formation velocity), triazolam (1‐OH TRZ IC50 1.1 mg dL−1, 4‐OH TRZ …−1) and testosterone (6β‐OH TST IC50 2.4 mg dL−1).
The Journal of pharmacy and pharmacology  •  2004  |  View Paper
Fatal poisoning involving coadministration of alcohol and benzodiazepine, especially triazolam , continues to be a serious problem.
Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology  •  2004  |  View Paper
Fatal poisoning involving coadministration of alcohol and benzodiazepine, especially triazolam , continues to be a serious problem.
Journal of toxicology. Clinical toxicology  •  2002  |  View Paper
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