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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Plasma T3 and T4 concentrations increased significantly during the period of ethanol administration compared with control values (ANOVA, P less than 0.005).”
One year of ethanol feeding increases circulating thyroid hormones in the dog.“Summary Although thyroxine and ethanol possess diuretic activity when administered alone, the administration of 8.5% ethanol to rats pretreated with 20 μg of thyroxine per day for 7 days abolishes the diuretic action of the thyroxine.”
“The mechanism by which ethanol blocks the diuretic action of thyroxine is not apparent from the available data.”
“ Ethanol feeding resulted in a slight decrease in T3 and T4 levels and a significant increase in thyroid-stimulating hormone concentration, which may be due to the direct stimulatory effect of ethanol on thyroid.”
Effect of Zinc Supplementation on the Status of Thyroid Hormones and Na, K, and Ca Levels in Blood Following Ethanol Feeding“ Ethanol per se caused an increase in transfer and accumulation of radiothyroxine or made the changes after loading animals with carrier T4 more pronounced.”
“Probably as a result, the tissue concentrations of T4 were higher in areas of the CNS in the groups exposed to alcohol.”
“We report here that young rats exposed to alcohol in utero have significantly lower serum total thyroxine ( T4 ) concentrations than normal and pair-fed control rats.”
“A tendency towards lipid peroxidation level decrease and to brain superoxide dismutase activity increase, as well as blood antioxidation activity increase (evaluated by transferrin and coeruloplasmin contents and by serum superoxide dismutase activity) and a decrease of thyroxine level were observed as a result of ethanol consumption.”
“The in vitro conversion of T4 to T3 increased significantly by adding ethanol 2% or carbamazepine (CBZ) 400 microM in ethanol 2% to the incubation medium.”
“In the view of the fact ethanol increases the blood-brain barrier permeability for thyroxine (T4) during a critical period of postnatal brain development in the rabbit, the influence of ethanol with or without T4 on cerebral RNA and DNA concentration has been investigated.”
“The changes provoked by T4 with ethanol were more pronounced when compared to those after T4 only.”
“Administration of thyroxine led to an increase in the rate of ethanol metabolism when measured both in vitro and in vivo.”
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