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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Studies with HuTu-80 cells chronically exposed to ethanol also showed a significant inhibition in carrier-mediated thiamin uptake.”
“These studies demonstrate that chronic alcohol feeding inhibits intestinal thiamin absorption via inhibition of the individual membrane transport event across the polarized absorptive epithelial cells.”
Chronic alcohol consumption and intestinal thiamin absorption: effects on physiological and molecular parameters of the uptake process.“It was established that ethanol ingestion produced a rapid decrease in blood thiamine levels and transketolase activity in erythrocytes and an increase in TPP effect in erythrocytes.”
“ Alcohol affects thiamine uptake and other aspects of thiamine utilization, and these effects may contribute to the prevalence of thiamine deficiency in alcoholics.”
“ Thiamin status evaluated by blood thiamin level and erythrocyte transketolase activity a thiamin dependent enzyme, decreased significantly by excess administration of alcohol.”
“In addition, there is evidence to suggest that alcohol reduces thiamine phosphorylation to thiamine pyrophosphate (TPP) in brain.”
“ Ethanol decreases thiamine absorption and decreases the enterohepatic circulation of folate.”
“Therefore, ethanol affecting active transport had a less effect on passive diffusion of thiamine.”
“ Thiamin deficiency and prenatal exposure to alcohol could act synergistically to produce negative effects on fetal development; however, this area of research is currently under-studied.”
“Supplementation of dietary intake of thiamine in people who are alcohol dependent remains an important measure for the prevention of Wernicke-Korsakoff's syndrome in this population.”
“ Thiamin can become depleted with the consumption of alcohol , coffee, tea, sulfites and many types of medications and conditions including blood sugar issues, Crohn’s and MS.”
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