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Last Updated: 3 years ago

Possible Interaction: Ethanol and Thiamine





Research Papers that Mention the Interaction

Studies with HuTu-80 cells chronically exposed to ethanol also showed a significant inhibition in carrier-mediated thiamin uptake.
These studies demonstrate that chronic alcohol feeding inhibits intestinal thiamin absorption via inhibition of the individual membrane transport event across the polarized absorptive epithelial cells.
American journal of physiology. Gastrointestinal and liver physiology  •  2010  |  View Paper
It was established that ethanol ingestion produced a rapid decrease in blood thiamine levels and transketolase activity in erythrocytes and an increase in TPP effect in erythrocytes.
Experientia  •  2005  |  View Paper
Alcohol affects thiamine uptake and other aspects of thiamine utilization, and these effects may contribute to the prevalence of thiamine deficiency in alcoholics.
Current molecular medicine  •  2001  |  View Paper
Thiamin status evaluated by blood thiamin level and erythrocyte transketolase activity a thiamin dependent enzyme, decreased significantly by excess administration of alcohol.
Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence  •  2000  |  View Paper
In addition, there is evidence to suggest that alcohol reduces thiamine phosphorylation to thiamine pyrophosphate (TPP) in brain.
Alcohol and alcoholism  •  1989  |  View Paper
Ethanol decreases thiamine absorption and decreases the enterohepatic circulation of folate.
Federation proceedings  •  1985  |  View Paper
Therefore, ethanol affecting active transport had a less effect on passive diffusion of thiamine.
Voprosy pitaniia  •  1980  |  View Paper
Thiamin deficiency and prenatal exposure to alcohol could act synergistically to produce negative effects on fetal development; however, this area of research is currently under-studied.
Biochemistry and cell biology = Biochimie et biologie cellulaire  •  2018  |  View Paper
Supplementation of dietary intake of thiamine in people who are alcohol dependent remains an important measure for the prevention of Wernicke-Korsakoff's syndrome in this population.
Alcohol and alcoholism  •  2013  |  View Paper
Thiamin can become depleted with the consumption of alcohol , coffee, tea, sulfites and many types of medications and conditions including blood sugar issues, Crohn’s and MS.
Nihon rinsho. Japanese journal of clinical medicine  •  1999  |  View Paper
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