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Last Updated: 3 years ago

Possible Interaction: Ethanol and Theophylline



Research Papers that Mention the Interaction

Theophylline pretreatment prior to acute ethanol administration markedly reduced the duration of ethanol-induced sleep and similarly decreased the intensity and duration of motor incoordination.
Life sciences  •  1983  |  View Paper
A monoamine oxidase inhibitor pargyline and an inhibitor of phosphodiesterase theophylline prevented the increase in adenylate deaminating activity in a subfraction of mitochondrial membranes in the ethanol intoxicated rats.
Voprosy meditsinskoi khimii  •  1976  |  View Paper
Mice reduced ethanol intake in the restricted access condition after receiving caffeine (20.0 mg/kg), or theophylline (20.0 mg/kg), another methylxanthine.
Pharmacology Biochemistry and Behavior  •  2019  |  View Paper
In contrast, when administered during ethanol withdrawal, theophylline (1-10 mg/kg) blocked the anti-hyperalgesic effects of ethanol during ethanol withdrawal, whereas nitrendipine (5-25 mg/kg) enabled ethanol to produce levels of antinociception comparable to non-dependent rats.
Progress in Neuro-Psychopharmacology and Biological Psychiatry  •  2006  |  View Paper
However, theophylline pretreatment significantly reduced ethanol-induced changes in beta-EN levels in HY, completely blocked ethanol effects in HI, and reversed ethanol alterations in MB.
Pharmacology  •  1995  |  View Paper
Ethanol (25 mM) blocked the stimulatory effect of theophylline and the results of experiments following the inclusion of adenosine deaminase suggested the involvement of adenosine in this effect of ethanol.
Life sciences  •  1989  |  View Paper
Theophylline pretreatment prevented the increase in Bmax elicited by ethanol.
Pharmacology Biochemistry and Behavior  •  1988  |  View Paper
The increase in osmotic water flow caused by vasopressin, theophylline or cyclic adenosine-3',5'-monophosphate was inhibited by 4 to 40 mg per ml of ethanol in the mucosal or serosal bathing medium.
The Journal of pharmacology and experimental therapeutics  •  1976  |  View Paper
Previous studies in this laboratory demonstrated that the rate of intestinal absorption of theophylline in rats is increased significantly by ethanol in low concentrations and that this absorption enhancing effect is associated with an increased net water flux from the intestine.
The results show that the theophylline absorption enhancing effect of ethanol is not limited to that particular alcohol.
Journal of pharmaceutical sciences  •  1975  |  View Paper
Abstract The purpose of this investigation was to deter mine directly the effect of ethanol on the absorption of theophylline from the small intestine of the rat.
It is concluded that the effect of ethanol on the intestinal absorption of theophylline is probably due to solvent drag, secondary to a change in water flux induced by alcohol.
Theophylline absorption and water net flux were significantly increased by 2% ethanol.
Theophylline absorption was significantly increased by 5% ethanol and decreased by 20% ethanol.
Journal of pharmaceutical sciences  •  1974  |  View Paper
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