Possible Interaction: Ethanol and Tetrahydrocannabinol (THC)

“Additionally, in women, but not in men, “disliking” alcohol was negatively correlated with “disliking” THC.”

“Unexpectedly, “wanting more” alcohol was inversely correlated with “wanting more” THC.”

“… alcohol was … THC , 38 % of the sample failed the test, and 35 % also failed when the high dose of alcohol was combined with a higher dose … highlight the limited ability of the SFST to identify drug consumption in the absence of any evidence of driving impairment or physiological indicators.”

“However, combined effects of THC and alcohol on divided attention were bigger than those by alcohol alone.”

“These data suggest that ethanol may increase the absorption of THC resulting in an increase in the positive subjective mood effects of smoked marihuana and contributing to the popularity of this drug combination.”

“ Ethanol produced significant decrements in standing steadiness and psychomotor coordination, while THC caused a significant deterioration in performance on all the four rotated factors.”

“ Ethanol was not very effective in in + uencing performance but this dose of THC produced marked decrements, predominantly in the latter part of the experiment.”

“The interaction between THC and ethanol was considered to be complex.”

“The peak blood ethanol concentration was higher (P=0·05) when subjects received both ethanol and THC than when they received ethanol alone.”

“Using subjects as their own controls, it was found that THC selectively enhanced the amplitude as compared to placebo while alcohol depressed it.”

“It was found that the high dose of THC produced Significant impairment in performance of both mental and motor tasks and that alcohol induced an additional effect.”

“This review will provide an overview of the data gathered using this model to show that chronic administration of two of the most commonly abused substances, alcohol and cannabinoids (Δ9-Tetrahydrocannabinol; THC ), affect host-pathogen interactions.”