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Last Updated: 2 years ago

Possible Interaction: Ethanol and Temazepam

supplement:

Ethanol

Research Papers that Mention the Interaction

Temazepam (15 mg) plus ethanol (peak blood concentration of 11 mmol·1−1) significantly impaired divided attention, tracking, and reaction time over a 3 h period.
The performance on the tracking, divided attention, and PAB reaction time tasks used in this study was impaired by a combination of Tmazepam and ethanol in doses which may not cause impairment when each is given alone.
European Journal of Clinical Pharmacology  •  2005  |  View Paper
The faster, more error-prone, behaviour on ethanol than with a similarly impairing dose of temazepam has clear implications for the relative potential of the two drugs to contribute to accidents.
Journal of psychopharmacology  •  2003  |  View Paper
The findings of the present study … that even a moderate amount of ethanol in combination with a … dose of triazolam or temazepam can cause performance impairment that might diminish an individual's ability to respond adequately … unexpected demands (e.g. smoke alarms or middle-of-the-night child care).
Journal of psychopharmacology  •  2002  |  View Paper
Temazepam potentiates the CNS depressant effect ofalcohol , and VIceversa.
The Medical journal of Australia  •  1987  |  View Paper
In addition to this pharmacological interaction, this report describes a novel chemical reaction between temazepam (a 3-hydroxy-1,4-benzodiazepine) and ethanol under acidic conditions similar to those found in vivo, resulting in a 3-ethoxylated product.
Journal of pharmaceutical sciences  •  1994  |  View Paper