supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Ethanol
supplement:
St John's Wort
Research Papers that Mention the Interaction
“During treatment alcohol intake was monitored .In present finding chronic administration of SJW significantly reduced ethanol intake by 78.6% (P<0.001) in mice.”
Chronic administration of St. John's Wort attenuates alcohol intake and brain indoleamine 2, 3-dioxygenase activity in mice.“ HPE (25–200 mg/kg) produced some dose‐dependent and significant inhibitory effects on locomotor hyperactivity at second and sixth hour of ethanol withdrawal.”
“These results suggest that HPE has some beneficial effects on ethanol withdrawal syndrome in rats.”
“AIMS Recent studies have shown that Hypericum perforatum extracts (HPE) inhibit ethanol intake in alcohol-preferring rats, but their mechanism of action is still unknown.”
“ Hypericum perforatum extracts (HPE) inhibit ethanol intake in rats.”
“Moreover, different neurochemical mechanisms are apparently responsible for the reduction of ethanol intake and for the antidepressant-like effect of HPE.”
“In rats offered 10% ethanol … 12 h/day, ethanol intake following treatment … 250 mg/kg HPE was significantly lower than that of controls for up to 10 h. The effect on ethanol intake was not related to the antidepressant-like effect of HPE revealed in the forced swimming test.”
“administration of HPE , 125 or 250 mg/kg, induced a 30-40% reduction in ethanol intake in rats offered 10% (v/v) ethanol for 2 h/day.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback