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Last Updated: 3 years ago

Possible Interaction: Ethanol and Spironolactone

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supplement:

Ethanol

drug:

Spironolactone

Research Papers that Mention the Interaction

“Seven days of spironolactone treatment was associated with reduction in ethanol intake (2.9 g/kg/24 hr), reduction in systolic blood pressure (5 mm Hg), and increase in sodium excretion (1 mmol/24 hr).”

“ Spironolactone , along with antihypertensive effect, decreases ethanol intake.”

Marinobufagenin in Urine: A Potential Marker of Predisposition to Ethanol and a Target for Spironolactone.

Current hypertension reviews • 2018 | View Paper

“In female rats spironolactone (50mg/kg) reduced alcohol self‐administration and persistence of alcohol responding.”

The mineralocorticoid receptor antagonist spironolactone reduces alcohol self-administration in female and male rats

Pharmacology Biochemistry and Behavior • 2018 | View Paper

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