Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Ethanol and Spermine

supplement:

Ethanol

Research Papers that Mention the Interaction

The activity shown by a series of commercially available polyamines (putrescine (Pu), spermidine (SPD) and spermine SP )) in inhibiting voluntary ethanol intake lends support to our hypothesis.
Journal of ethnopharmacology  •  2006  |  View Paper
Recent evidence suggests that elevations in the synthesis and release of the polyamines spermidine and spermine , which are known modulators of NMDARs, contribute to the increased activity of the receptor during ethanol withdrawal.
Alcoholism, clinical and experimental research  •  2003  |  View Paper
The levels of spermidine and spermine decreased by long-term administration of alcohol , but the effect of VE deficiency was not found.
Alcoholism, clinical and experimental research  •  1996  |  View Paper
The effects of ethanol on Ca2+ uptake and Ca2+ efflux were antagonized by Mg2+, P(i) and spermine.
The Biochemical journal  •  1995  |  View Paper
Oral administration of cadaverine, spermidine and spermine prevented the lesion formation by acidified ethanol in a dose-dependent manner.
Japanese journal of pharmacology  •  1983  |  View Paper
The authors found that DNA denatures as ethanol concentration is increased and spermine concentration decreased.
Biopolymers  •  2012  |  View Paper