Possible Interaction: Ethanol and Sorbitol

“The effects of sorbitol , fructose and elevated concentrations of glucose were partly inhibited by ethanol , glycerol and glucosamine.”

“The amounts of formate and ethanol were greater in the suspensions incubated with sorbitol than with glucose.”

“ Ethanol and glycerol inhibited the effects of fructose, sorbitol and glucose on glucokinase translocation, whereas dihydroxy-acetone had a small additive effect at sub-maximal substrate stimulation.”

“Crotonol and ethanol inhibited glucose production from glycerol, xylitol, and sorbitol , suggesting that changes in the cytosolic redox state play the major role in the effect of the alcohols on glucose production from these substrates.”

“ Ethanol stimulated glucose production from pyruvate, while inhibiting gluconeogenesis from glycerol, xylitol and sorbitol.”

“Abstract In isolated rat liver cells, ethanol inhibited gluconeogenesis from xylitol and sorbitol but not from fructose.”

“These data indicate that the inhibitory action of ethanol on glucose production from xylitol and sorbitol can be reproduced by physiological concentrations of acetaldehyde.”

“Abstract Previous investigations have shown that sorbitol delays the rate of ethanol oxidation and conversely that ethanol inhibits the oxidation of sorbitol.”

“The mechanism by which ethanol and sorbitol inhibit each other's oxidation is suggested to be competition for free NAD+.”

“Fructose increased and sorbitol significantly decresed the acetaldehyde level of hepatic venous blood in euthyroid animals given ethanol.”

“ Ethanol inhibited sorbitol elimination by 60 per cent in hypothyroid animals, by 39 per cent in controls and by 16 per cent in hyperthyroid rats.”

“The addition of sorbitol decreases the lag phase and increases ethanol yield and productivity of the bacteria in high glucose concentrations.”