supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Ethanol
drug:
Simvastatin
Research Papers that Mention the Interaction
“Administration of hypolipidemic agent simvastatin simultaneously with ethanol and CC14 resulted in decrease liver fat accumulation, fibrosis and peroxidation products.”
[Hepatocyte mitochondrion respiratory chain in rats with experimental toxic hepatitis].“Simultaneous injection of simvastatin (1 mg/kg, intragastrically) in rats with ethanol --CCl4 hepatitis decreased fatty dystrophy and produced certain anticytolytic and anticholestatic effects without potentiation of microsomal oxidation system damage by hepatotoxins.”
“The current study demonstrated that administration of simvastatin significantly attenuates spatial memory impairment (P< 0.01) after ethanol neurotoxicity.”
Simvastatin attenuates spatial memory impairment via inhibiting microgliosis and apoptotic cell death against ethanol induced neurotoxicity in the developing rat hippocampus
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback