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“According to open studies the long-term administration of silymarin significantly increased survival time of patients with alcohol induced liver cirrhosis.”
“ Alcohol also increased hepatic collagen type I by 50% over the 3 years with a significant rise in mRNA for &agr;1 (I) procollagen, both prevented by silymarin.”
Journal of clinical gastroenterology • 2003 | View Paper
“We explored the possibility that silymarin (SY), a fraction from Silybum marianum, might protect against the effects of in utero exposure to ethanol upon subsequent social memory function.”
“The hepatoprotective and antioxidant activity of silymarin is caused by its ability to inhibit the free radicals that are produced from the metabolism of toxic substances such as ethanol , acetaminophen, and carbon tetrachloride.”