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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Ethanol induced dephosphorylation of GSK3β at Ser9 and the activation of Bax as well as caspase‐3 in the developing mouse brain.”
Overexpression of glycogen synthase kinase 3β sensitizes neuronal cells to ethanol toxicity“Differences between strains were also observed in the alteration of serine , alanine and isoleucine concentrations produced by chronic administration of ethanol.”
“We found that exposure of NCCs to ethanol resulted in the increases in the total protein levels of p53 and the phosphorylation of p53 at serine 15.”
Up-regulation of Siah1 by ethanol triggers apoptosis in neural crest cells through p38 MAPK-mediated activation of p53 signaling pathway“ Alcohol robustly increased protein kinase A-mediated phosphorylation of GluA1 at serine 845 in multiple regions.”
“ Ethanol inhibited neurite outgrowth by activating GSK3β through the dephosphorylation of GSK3β at serine 9.”
“These findings suggest that acute ethanol administration alters PKC synthesis and translocation in an isoform and brain region specific manner that leads to alterations in serine phosphorylation of receptors.”
“Treatment of freshly isolated adult rat hepatocytes with 10–100 mM ethanol rapidly (<3 min) inhibits interleukin‐6 (IL‐6)‐induced STAT3 activation, tyrosine and serine phosphorylation and IL‐6‐induced CCAAT enhancer binding protein (C/EBP) α and β mRNA expression.”
“ Ethanol lowered the concentration of most plasma amino acids (AA) or related compounds in stressed rats (e.g., aspartic acid, threonine, serine , glycine, alanine, valine, tyrosine, phenylalanine, tryptophan).”
“In hepatocytes from fed rats alanine, asparagine, cysteine, glycine, hydroxyproline, ornithine and serine still increase ethanol oxidation, although to a lesser extent than in cells from starved rats.”
“In hepatocytes from starved rats, asparagine, serine , ornithine, hydroxyproline, histidine, cysteine, alanine, glycine, glutamate, glutamine, aspartate and arginine significantly increase ethanol consumption.”
“In hepatocytes from fasted rats, alanine, arginine, asparagine, aspartate, citrulline, cysteine, glutamate, glutamine, glycine, histidine, hydroxyproline, ornithine and serine increase significantly ethanol consumption.”
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