Possible Interaction: Ethanol and Selenium

“Furthermore, prenatal and postnatal exposure to ethanol in dams, as well as increasing oxidation in offspring, causes malnutrition of several micronutrients such as the antioxidant folic acid and selenium ( Se ), affecting their metabolism and bodily distribution.”

“Increased selenium concentrations were associated with intake of whale meat, alcohol abstention , delivery after term, and high parity.”

“In both rapid and slow acetylators the apparent half life of the drug decreased by about 20% after ethanol (mean reduction 39 +/- SE 8 min) and the amount of drug acetylated, measured in blood and urine, increased.”

“ Ethanol extracts exhibited fungistatic but not fungicidal activity against a range of micromycetes, and mycelium enrichment with selenium inhibited this effect.”

“Children exposed to alcohol during prenatal development were significantly impaired in olfactory identification (M = 5.95, SE = 0.37) compared to typically developing controls (M = 7.24, SE = 0.37).”

“In conclusion, heavy consumption of ethanol reduced plasma levels of alpha-tocopherol, selenium and 25-hydroxyvitamin D3.”

“The selenium and SeNPs could also prevent pericardial edema induced ethanol treatment and reduced apoptosis and cell death in zebrafish embryos.”

“ Ethanol exposure during gestation and lactation decreases selenium (Se) intake, disrupting body Se balance and inducing oxidative stress in rat offspring.”

“Histological data showed that 100 μg/kg selenium distinctly reduced the depth and severity of the ethanol induced gastric lesion.”

“AIMS Levels of antioxidants such as folic acid and selenium decrease in dams exposed to ethanol during gestation and lactation, affecting their antioxidant status, their reproductive function and consequently the health of their progeny.”

“RESULTS Results show that et anol de creases Se re tention in dams, affecting their tissues' Se deposits, decreasing serum GPx activity, gestational parameters and the weight of their progeny.”