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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Risperidone
Research Papers that Mention the Interaction
“ Risperidone also reduced dose-dependently locomotor activity and limited access saccharin intake of the AA rats, indicating that its effect on ethanol drinking was not selective.”
“ Risperidone at 0.1 mg/kg given before four successive daily ethanol-drinking sessions significantly reduced the ethanol intake.”
Risperidone reduces limited access alcohol drinking in alcohol-preferring rats.“On the other hand, a high risperidone dose (10 mg/kg/day, SC, for 14 days), which produces pronounced dopamine D2 receptor blockade, reduced 8% ethanol preference, like the dopamine receptor antagonist haloperidol.”
“The lowest dose of risperidone (0.1 mg/kg) evoked marked inhibition of ethanol drinking, similar (slow onset, but long-lasting effect) to that produced by the 5-HT2 receptor antagonist ritanserin, 1 mg/kg, SC.”
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