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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Raclopride
Research Papers that Mention the Interaction
“SCH 23390, but not raclopride , prevented lowering of BSR threshold by alcohol in DBA mice.”
Different Contributions of Dopamine D1 and D2 Receptor Activity to Alcohol Potentiation of Brain Stimulation Reward in C57BL/6J and DBA/2J Mice“Previous research that used a fixed-ratio schedule of responding maintained by the presentation … small dippers (0.1 ml) of ethanol demonstrated that the dopamine D2 antagonist, raclopride , decreased total responding for ethanol by both delaying the onset of responding and causing the early termination of lever-press behavior.”
“Both raclopride and d-amphetamine administration produced reductions in ethanol consumption (in comparison to saline treatment).”
“Coadministration of raclopride blocked the quinpirole-induced increase in response latency ( ethanol reinforcement) and decrease in response rate (sucrose reinforcement), but had no effect on other response measures.”
“ Raclopride (0.05 and 1.0 microgram/microliter) decreased total ethanol responding and rate, but doses as much as 400-fold greater (20.0 micrograms/microliter) did not alter sucrose response totals.”
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