Possible Interaction: Ethanol and Psychotropic Drugs

“Participants were asked to refrain from use of illicit psychoactive drugs for at least 7 days and ethanol for at least 48 hours before testing.”

“ Alcohol is known to interact with psychotropes , often to potentiate their central effects.”

“The importance of testing for interaction between the commonly prescribed psychotropic agents and alcohol is discussed since potentiation of alcohol effects may at times contribute to traffic accidents and the hazards of drug overdosage.”

“Non-genetic constitutional and environmental factors, including age, sex, disease states, smoking or alcohol habits and concurrent drug administration, are important elements which influence the metabolism of psychotropic drugs.”

“An estimate is given of the relative potency of different psychotropic agents (which are being ever more widely prescribed) in adding to the effects of alcohol.”

“Late (delayed) deaths, recently recorded in humans and animals, may be associated with the inhibition of gastro‐intestinal motility by ethical psychotropic agents , particularly when taken together with alcohol.”

“5 It is suggested that the potentiation of alcohol by some psychotropic drugs may add to the hazards of drug overdosage and contribute to traffic accidents.”

“In addition, the long-term side effects of psychotropic drugs (metabolic syndrome, extrapyramidal symptoms, electrolyte imbalance, etc), physical health problems (obesity, gynecomastia, sexual dysfunction, etc), substance use disorders (nicotine, alcohol , marijuana, etc), and medication non-adherence are other important problems in the fight against …”

“INTRODUCTION AND AIMS Prescribed psychotropic medications contribute to overdose mortality among people with alcohol and other drug (AOD) disorders.”

“A particular attention was paid to eliminate the concomitant alcohol or psychotropic co-ingestions.”