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Last Updated: 3 years ago

Possible Interaction: Ethanol and Progesterone





Research Papers that Mention the Interaction

Alcohol also increased pregnenolone (PREG) and dehydroepiandrosterone (DHEA) concentrations, while it decreased progesterone (PROG) and allopregnanolone (ALLO) concentrations, as well as ALLO/PREG and PROG/PREG ratios.
Psychopharmacology  •  2005  |  View Paper
Among subjects not using oral contraceptives, progesterone levels decreased after intake of alcohol (0.5 g/kg).
Alcoholism, clinical and experimental research  •  1999  |  View Paper
ConclusionsThis is the first study to show that normal menstrual cycle fluctuations in progesterone , particularly during the late luteal phase, can modulate ethanol intake.
Psychopharmacology  •  2019  |  View Paper
BACKGROUND Acute ethanol administration increases plasma and brain levels of progesterone and deoxycorticosterone-derived neuroactive steroids (3alpha,5alpha)-3-hydroxypregnan-20-one (3alpha,5alpha-THP) and (3alpha,5alpha)-3,21-dihydroxypregnan-20-one (3alpha,5alpha-THDOC) in rats.
Alcoholism, clinical and experimental research  •  2010  |  View Paper
Furthermore, it has been reported that plasma levels of estradiol, progesterone and testosterone increase during alcohol treatment in the midluteal phase, while gonadotropins tend to decrease.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement  •  1987  |  View Paper
The presence of 1-8% (vol/vol) ethanol enhanced specific LH binding to macaque luteal particulates under steady state conditions (25 C, 20-h incubation), with a maximal effect at 8% ethanol (166% of control uptake; P less than 0.05).
Endocrinology  •  1985  |  View Paper
Ethanol lowered the mean testicular concentrations of testosterone (by 63–74%), androstenedione (49–81%), 17‐hydroxyprogesterone (60–76%), progesterone (29–67%) and pregnenolone (12–25%).
FEBS letters  •  1984  |  View Paper
One well-controlled study in 1987 did generate renewed interest in the area with the paradoxical finding that progesterone actually enhanced alcohol elimination at low blood concentrations (<.025%).
Journal of studies on alcohol  •  2005  |  View Paper
These studies, emanating from the same laboratory, found that alcohol elimination increased, by about 14%, during the luteal phase compared to other phases of the cycle.
Addiction  •  1995  |  View Paper
Ethanol concentrations at 34.6 and 69.2 mmol/L significantly increased and progesterone concentration at 32 mumol/L significantly decreased the monoamine oxidase activity.
American journal of obstetrics and gynecology  •  1993  |  View Paper
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