“Finally, probucol inhibited activation of the extracellular signal‐regulated kinase signalling pathway induced by ethanol + CCl4.”
“Moreover, probucol markedly suppressed increases in oxidative stress, ECM protein accumulation and cytokine production induced by ethanol + CCl4.”
“Our findings reveal that probucol attenuates ethanol + CCl4‐induced liver fibrosis by inhibiting oxidative stress, ECM protein accumulation and cytokine production.”
“ Probucol significantly attenuated the histological changes induced by ethanol + CCl4 and improved liver function.”