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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Pregabalin
Research Papers that Mention the Interaction
“Pilotstudies on alcohol- and benzodiazepine dependent patients reported a reduction of withdrawal symptoms through Pregabalin.”
[Pregabalin for the reduction of opiate withdrawal symptoms].“Benzodiazepines, clomethiazole, tiagabine, vigabatrin, pregabalin , gabapentin, acamprosate, naltrexone, GHB, topiramate, ondansetron and baclofen at low dose (≤1 mg/kg, the dose range used in randomized trials in humans: 30 and 60 mg/day) have all been shown to at best reduce motivation to consume alcohol in rats.”
“This effect was confirmed in self-administration experiments where pregabalin (0, 10 and 30 mg/kg) significantly reduced operant responding for alcohol but not for food.”
Pregabalin reduces alcohol drinking and relapse to alcohol seeking in the rat
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