Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Ethanol and Piroxicam

supplement:

Ethanol

Research Papers that Mention the Interaction

The permeation rate of piroxicam increased proportionally with ethanol concentration but decreased with polymer concentration.
International journal of biological macromolecules  •  2013  |  View Paper
It has been reported that piroxicam prevents the hepatic increase of triacylglycerides and thiobarbituric acid-reactive substances observed after acute ethanol intoxication in rats and also causes a decrease in blood ethanol concentration.
Thus, piroxicam helps to control the oxidative stress produced in isolated hepatocytes by ethanol.
European journal of pharmacology  •  1996  |  View Paper
As previously reported for fasted rats, piroxicam in fed rats decreases the concentration of ethanol in blood and inhibits the hepatic increase of triacylglycerols and malondialdehyde consequent to ethanol administration.
In addition, the hepatic depletion of reduced and reduced plus oxidized glutathione observed 8 and 12h after gavage of ethanol was reversed when piroxicam was administered simultaneously with ethanol.
Life sciences  •  1994  |  View Paper
The non‐steroidal anti‐inflammatory drug, piroxicam , prevents the hepatic increase of triacylglycerols and malondialdehyde resulting from the acute intoxication of rats with ethanol.
FEBS letters  •  1992  |  View Paper
Oleic acid, ethylacetate, and ethanol promoted the diffusion of Pir.
Zhongguo yao li xue bao = Acta pharmacologica Sinica  •  1991  |  View Paper