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Last Updated: 2 years ago

Possible Interaction: Ethanol and Pindolol

supplement:

Ethanol

Research Papers that Mention the Interaction

We have previously shown that systemic administration of the dual beta‐adrenergic antagonist and 5‐HT1A/1B partial agonist pindolol selectively reduces long‐term but not short‐term binge‐like consumption of ethanol and alters excitatory postsynaptic currents in basolateral amygdala (BLA) principal neurons.
We show that intra‐BLA infusion of pindolol (1000 pmol/0.5 μl), RU24969 (0.3 and 3 pmol/0.5 μl) and CGP12177 (500 pmol/0.5 μl) produce robust decreases in long‐term ethanol consumption.
Addiction biology  •  2019  |  View Paper
We show that the efficacy of pindolol to reduce ethanol consumption is enhanced following long‐term (12 weeks) binge– ethanol intake, compared with short‐term (4 weeks) intake.
Addiction biology  •  2017  |  View Paper