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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“ Chronic ethanol produced a decrease of compensatory augmentation of dopamine in rat's CNS after pimozide administration.”
[The role of dopamine neurotransmission on the development of ethanol dependence and course of abstinence syndrome].“The effect of ethanol on the startle response was potentiated by pretreatment of the animals with pimozide , haloperidol, and p-chlorophenylalanine but not by propranolol, phenoxybenzamine, alpha-methyltyrosine, or pargyline.”
“The degree to which pimozide attenuated ethanol excitation decreased with increasing ethanol dosage.”
Differential effects of catecholamine antagonists on ethanol-induced excitation in mice“In NH animals, pimozide attenuated excitation in inverse relation to the ethanol dosage.”
“ Pimozide (PIM), a dopaminergic antagonist, dose-relatedly decreased intakes of ES and water, and responding for positively reinforcing intracranial stimulation (ICS).”
“This suggests that pimozide produced inhibition of L-ADH in another species and thereby causing aversion to ethanol drinking or may be related to dopaminergic antagonist property.”
“Eight hours after a single (3 g/kg) dose of ethanol , DOPA synthesis was increased and pimozide , a dopamine receptor antagonist, stimulated DOPA synthesis to the same degree in ethanol‐treated and control animals.”
“It was found that both AMPT and pimozide blocked the acquisition of the CTAs normally produced by morphine and ethanol.”
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