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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Ethanol
supplement:
Phosphatidylethanolamine
Research Papers that Mention the Interaction
“Challenging intact erythrocytes from normal human subjects with ethanol resulted in dose-dependent decreases in rates of acylation of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) while triacylglycerol (TAG) acylation was stimulated.”
“On abstinence from alcohol after a period of heavy drinking, CDT and PEth concentrations could remain increased for several weeks up to approximately 1 month.”
Phosphatidylethanols in breath: a possible noninvasive screening test for heavy alcohol consumption.“In the presence of ethanol, phosphatidyl-ethanol is generated at the expense of PA leading to the suppression of mTOR.”
“The amounts of phosphatidyl-ethanol and phosphatidic acid formed were dependent on the concentration of ethanol.”
“In cells labeled with L-lyso-3-PC 1-[1- 14C]palmitoyl, PLD but not IL-4, increased the production of phosphatidic acid (PA) and phosphatidyl-ethanol when pretreated with ethanol.”
“Addition of ethanol inhibited both secretion and [3H]PA formation and led to the accumulation of [3H]phosphatidylethanol ([3H]PEt), indicating that [3H]PA was formed largely by activation of PLD.”
“We found that ethanol downregulated microglial NAPE-PLD expression by activating cAMP/PKA and ERK1/2.”
“Chronic treatment of adult male rats with ethanol liquid diets resulted in alterations in phospholipid and cholesterol contents as well as the acyl composition of phosphatidylethanolamine ( PE ), phosphatidylinositol (PI)-phosphatidylserine (PS) mixture, and phosphatidylcholine (PC) of isolated hepatocytes.”
Effects of ethanol diets on cholesterol content and phospholipid acyl composition of rat hepatocytes“ Chronic ethanol ingestion is known to increase the methylation of phosphatidylethanolamine (PE); therefore, in order to decrease PC, the increase in C.O. in the low-fat males must have been of sufficient magnitude to offset the increase in PE methylation.”
“The inhibition of PE synthesis by ethanol caused a decrease in its distribution in both inner and outer leaflets.”
“The synthesis of phosphatidylserine (PS) and phosphatidylethanolamine PE ) by base-exchange reaction (BES) was inhibited in membranes exposed to ethanol in direct response to its concentration.”
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