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Last Updated: 2 years ago

Possible Interaction: Ethanol and Phenylephrine



Research Papers that Mention the Interaction

The pressor responsiveness was also influenced differently by ethanol depending on the method of injecting phenylephrine.
Clinical science  •  1987  |  View Paper
In the presence of ethanol, phenylephrine stimulated phosphatidylethanol formation in α1A- and α1B-adrenoceptor-expressing cells time and concentration dependently but only weakly and inconsistently in α1D-adrenoceptor-expressing cells.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  1998  |  View Paper
Pretreatment with ethanol dose-dependently increased the potency of phenylephrine to induce vasoconstriction 4-fold (p<0.01).
PloS one  •  2019  |  View Paper
Intra‐pVTA administration of phenylephrine (alpha‐1 adrenoceptor agonist) increased ethanol self‐administration, while prazosin and disulfiram (agents that reduce noradrenergic tone) produced opposite effects.
Addiction biology  •  2017  |  View Paper
Moreover, combined treatment with testosterone and ethanol reduced the pressor response to the selective α1-adrenoceptor agonist phenylephrine.
PloS one  •  2016  |  View Paper
Ethanol significantly attenuated the contractions to phenylephrine and KCl.
European journal of pharmacology  •  2015  |  View Paper
Prazosin (0.1; 0.5 and 1.0 mg/kg) and phenylephrine (1.0 and 2.0 mg/kg) administration blocked the expression of behavioral sensitization to ethanol.
Behavioural Brain Research  •  2013  |  View Paper
The group treated with ethanol showed a decrease in vas deferens contractility to noradrenaline, phenylephrine , and barium, by less than 20%.
European journal of pharmacology  •  2012  |  View Paper
Chronic ethanol consumption increased the contractile response to phenylephrine of endothelium‐intact and denuded rat aortic rings from rats pretreated with ethanol for 2 or 6 weeks.
Six weeks' ethanol consumption enhanced the contractile response to phenylephrine of endothelium‐intact, but not denuded rat MAB.
The Journal of pharmacy and pharmacology  •  2007  |  View Paper
Vascular responsiveness to the pressor agent phenylephrine was initially enhanced and later on decreased during chronic ethanol intake.
Life sciences  •  2006  |  View Paper
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