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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Ethanol
drug:
Phenoxybenzamine
Research Papers that Mention the Interaction
“ Phenoxybenzamine produced a dose-dependent reduction in ethanol excitation.”
Differential effects of catecholamine antagonists on ethanol-induced excitation in mice“ Phenoxybenzamine , an alpha blocker disrupted the cycle and elevated ethanol to fatal levels.”
“It has been shown in the experiments on rats that subcutaneous administration of … alpha-adrenoblockers IEM-611 (30 mg/kg and 15 mg/kg) and phenoxybenzamine (10 mg/kg) for one or two … brings about a decrease in voluntary ethanol consumption at early stages of … alcoholism (3-week alcoholization).”
“Moreover, the increase in hepatic oxygen uptake produced by 2.5 h of ethanol treatment could be blocked by either alpha-(phenoxybenzamine ; 40 mg/kg) or beta-(propranolol; 40 mg/kg) adrenergic blocking agents.”
“Pretreatment with iproniazid (100 ing/kg) or phenoxybenzamine (10 mg/kg) failed to enhance or to block, respectively, the initial elevation in oxygen consumption induced by ethanol.”
THE EFFECT OF ETHANOL ON THE METABOLIC RATE OF RATS.
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