Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Ethanol and Pentobarbital



Research Papers that Mention the Interaction

Direct activation of the GABAA receptor by pentobarbital was enhanced by chronic ethanol treatment.
The Journal of pharmacology and experimental therapeutics  •  1998  |  View Paper
Thus, the type of expression/assay system markedly affects the actions of ethanol on GABAA receptors and also influences the actions of muscimol and pentobarbital on this receptor.
Alcoholism, clinical and experimental research  •  1997  |  View Paper
Pentobarbital and diazepam completely suppressed ethanol withdrawal reactions.
Japanese journal of pharmacology  •  1982  |  View Paper
In UChA, but not in the UChB rats, the chronic treatment with ethanol induced tolerance to pentobarbital as shown by the same test.
Pharmacology Biochemistry and Behavior  •  1981  |  View Paper
Ethanol inhibited the uptake in a concentration-dependent manner over the range … to 720 mM. Analysis of the effects of ethanol and pentobarbital on calcium uptake at different temperatures indicated that the drugs did not change … activation energy of the process but shifted the Arrhenius curves toward higher temperatures.
The Journal of pharmacology and experimental therapeutics  •  1980  |  View Paper
6 Animals withdrawn following chronic administration of a number of drugs, barbitone, barbitone/bemegride mixture, Mandrax (methaqualone: diphenhydramine; 10: 1), chlordiazepoxide, nitrazepam, chlorpromazine or ethanol , exhibited a significant tolerance to intracerebroventricularly administered pentobarbitone.
British journal of pharmacology  •  1974  |  View Paper
Ethanol ingestion significantly retarded the disappearance of pentobarbital and meprobamate from the blood in human volunteer subjects and rats.
The American journal of medicine  •  1970  |  View Paper
In vitro ethanol inhibited aniline, pentobarbital , and benzpyrene hydroxylases.
Science  •  1968  |  View Paper
In 15 mM K+, ethanol has no effect by itself but enhances the stimulatory effect of 0.01 mM pentobarbital.
The Journal of pharmacology and experimental therapeutics  •  1967  |  View Paper
It has been shown, for example, that in fatal poisonings involving dextropropoxyphene, amitriptyline, pentobarbitone or chlormethiazole, the presence of ethanol causes a decrease in the concentration of the drug at which a given proportion of fatalities
Human toxicology  •  1983  |  View Paper
Show More