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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Ethanol
drug:
Pentagastrin
Research Papers that Mention the Interaction
“After ingestion of alcohol , the volume of gastric juice in response to pentagastrin stimulation was reduced by 24.6%, as compared with the control period.”
“ Alcohol also significantly (-28%) inhibited the secretion of 6-keto-PGF1 alpha in the period following the administration of pentagastrin.”
“Ingestion of alcohol led to a significant reduction in the concentration of prostaglandin E2 (-42.7%) after stimulation with pentagastrin.”
“The prostaglandin E2 output per hour was markedly inhibited by the ingestion of alcohol , both in the basal period (-47%) and after stimulation with pentagastrin (-55%).”
Effect of acute ethanol ingestion on human gastric luminal prostaglandin E2, prostaglandin F2 alpha and 6-keto-prostaglandin F1 alpha.“At the concentration of 10% ethanol strongly inhibited the gastric acid secretion, stimulated by carbachol, histamine or pentagastrin.”
Studies on the mechanism of the inhibitory effect of ethanol on the gastric acid output in the rat“The protective activity of CCK and pentagastrin against ethanol injury was accompanied by a significant increase in gastric blood flow.”
“Certain drugs, such as histamine and pentagastrin , stimulated acid secretion but inhibited the injury to the mucosa by ethanol indicating that increased cellular activity could occur during the development of mucosal injury.”
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