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Last Updated: 3 years ago

Possible Interaction: Ethanol and Pantothenic Acid




Pantothenic Acid

Research Papers that Mention the Interaction

On the contrary, in rats fed a diet containing a low-vitamin mixture, consumption of ethanol caused a decrease in the contents of vitamins B₁, B₂ and pantothenic acid in the liver; however, the contents of the other vitamins did not decrease.
The British journal of nutrition  •  2012  |  View Paper
Ethanol consumption alters the levels and distribution of pantothenic acid and its metabolic products, an effect that can be counteracted by preloading with pantothenic acid.
Pantothenic acid (200 mg/kg, IP or IV) administered before ethanol intubation completely counteracted the tremor-reducing action of ethanol in two monkeys and partially counteracted it in a third.
Journal of studies on alcohol  •  1992  |  View Paper
3 PA concentration in the brain of rats treated with ethanol plus PA for 4 months was three times that of rats treated with ethanol alone.
6 Data suggest that chronic ethanol exposure may decrease ACh synthesis by depleting PA , a precursor for the synthesis of acetyl CoA. Acetyl CoA is an essential substrate for ACh synthesis.
ACh synthesis in rats with ethanol and PA supplementation was also significantly (P <0.01) higher.
British journal of pharmacology  •  1988  |  View Paper