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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Oxymorphone
Research Papers that Mention the Interaction
“Coadministration of oxymorphone ER or oxymorphone CRF with ethanol 20 and 40% increased oxymorphone peak plasma concentrations (C(max)) by 14 to 80% and reduced time to C(max).”
“For both formulations, oxymorphone area under the curve and terminal half-life were largely unaffected, but C(max) increased with ethanol dose.”
“These results provide reassurance about the integrity of oxymorphone ER formulations with ethanol.”
The effects of ethanol on the bioavailability of oxymorphone extended-release tablets and oxymorphone crush-resistant extended-release tablets.“However, a third report suggests that alcohol does increase peak oxymorphone concentrations.”
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