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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Ethanol and Oxymorphone



Research Papers that Mention the Interaction

Coadministration of oxymorphone ER or oxymorphone CRF with ethanol 20 and 40% increased oxymorphone peak plasma concentrations (C(max)) by 14 to 80% and reduced time to C(max).
For both formulations, oxymorphone area under the curve and terminal half-life were largely unaffected, but C(max) increased with ethanol dose.
These results provide reassurance about the integrity of oxymorphone ER formulations with ethanol.
The journal of pain : official journal of the American Pain Society  •  2012  |  View Paper
However, a third report suggests that alcohol does increase peak oxymorphone concentrations.
Journal of clinical psychopharmacology  •  2007  |  View Paper