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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“In addition to a sedative effect the interaction of alcohol and oxazepam in the oxazepam trial results in dysphoric changes of mood and related significant alterations of polarity profiles.”
[Psychopharmacologic studies on the combined effect of alcohol and oxazepam on reactivity pattern. II. Subjective feeling and reaction behavior].“Pretreatment of rats with ethyl alcohol increased significantly the concentration of the hydroxylated metabolite, free oxazepam , in the plasma, but not of the demethylated metabolite, N-demethyldiazepam.”
“The concomitant influence of ethanol and oxazepam accentuates the motoric instability with a delay of the motoric responses.”
“The results indicate the existence of marked interactions between ethanol and oxazepam.”
“ Ethanol pretreatment resulted in rapid cross-tolerance, on both tests, to the various alcohols (n-propanol, n-butanol, and t-butanol) and the benzodiazepines (chlordiazepoxide, diazepam, oxazepam , and flurazepam) tested.”
Rapid tolerance and cross-tolerance as predictors of chronic tolerance and cross-tolerance“ Ethanol reduced oxazepam levels but increased desmethyl diazepam levels, suggesting that 3‐hydroxylation of desmethyl diazepam was inhibited by ethanol.”
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