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Last Updated: 2 years ago

Possible Interaction: Ethanol and Omeprazole



Research Papers that Mention the Interaction

The testosterone levels before and after ethanol following omeprazole therapy rose an average of 55.4 ng/dL (n = 8; p = NS).
Journal of toxicology. Clinical toxicology  •  1997  |  View Paper
The oral administration of CPRHE at doses of 200 mg/kg and 400 mg/kg and omeprazole (positive control) at a dose of 20 mg/kg to rats remarkably attenuated gastric lesions induced by ethanol.
BMC Complementary and Alternative Medicine  •  2014  |  View Paper
In omeprazole pretreated rats, gavage with ethanol resulted in a significant twofold worsening of duodenal injury.
Thus chronic administration of omeprazole appears to increase the susceptibility of the duodenal mucosa to ethanol injury in rats.
Digestive Diseases and Sciences  •  2005  |  View Paper
A coupling between secretory and metabolic effects induced by ethanol (demonstrated by an inhibitory effect of omeprazole in both parameters) was found.
Experimental biology and medicine  •  2003  |  View Paper
Cimetidine, but not omeprazole , reduced ethanol metabolism by 39.9% +/- 4.9% (P < 0.01), an inhibition comparable with that previously reported for first-pass metabolism in vivo.
Gastroenterology  •  1995  |  View Paper