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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Ethanol
drug:
Omeprazole
Research Papers that Mention the Interaction
“The testosterone levels before and after ethanol following omeprazole therapy rose an average of 55.4 ng/dL (n = 8; p = NS).”
Does concurrent acute ethanol ingestion during omeprazole therapy affect pituitary gonadal axis in male subjects?“The oral administration of CPRHE at doses of 200 mg/kg and 400 mg/kg and omeprazole (positive control) at a dose of 20 mg/kg to rats remarkably attenuated gastric lesions induced by ethanol.”
Evaluation of acute toxicity and gastroprotective activity of curcuma purpurascens BI. rhizome against ethanol-induced gastric mucosal injury in rats“In omeprazole pretreated rats, gavage with ethanol resulted in a significant twofold worsening of duodenal injury.”
“Thus chronic administration of omeprazole appears to increase the susceptibility of the duodenal mucosa to ethanol injury in rats.”
“A coupling between secretory and metabolic effects induced by ethanol (demonstrated by an inhibitory effect of omeprazole in both parameters) was found.”
“Cimetidine, but not omeprazole , reduced ethanol metabolism by 39.9% +/- 4.9% (P < 0.01), an inhibition comparable with that previously reported for first-pass metabolism in vivo.”
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