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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Ethanol
supplement:
Oil Of Garlic
Research Papers that Mention the Interaction
“In the in vitro study, human normal cell LO2 was exposed to 100 … in the presence or absence of GO for 24 h. We found that ethanol increased the protein levels of n-SREBP-1c and CYP2E1, but … protein levels of PPAR-α, which was significantly attenuated by GO ….”
Garlic oil alleviated ethanol-induced fat accumulation via modulation of SREBP-1, PPAR-α, and CYP2E1.“These data indicated that single dose of GO possessed ability to prevent acute ethanol-induced fatty liver, but may lose its capacity when used after ethanol exposure.”
“However, when ethanol mixed with 0.5% garlic oil was fed to animals maintained on the high fat-high cholesterol diet, these lipid levels were significantly reduced to levels near to those seen in untreated control rats.”
“Pretreatment with garlic oil in doses of 0.25 and 0.5 mg/kg, 30 min before administration of ethanol (1 mL of 100%) caused a decrease in ulcer index and lipid peroxidation and ameliorated the decrease in antioxidant enzyme levels caused by ethanol.”
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