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Last Updated: 3 years ago

Possible Interaction: Ethanol and Nomifensine



Research Papers that Mention the Interaction

We have observed that chronic daily exposure to a relatively high dose of alcohol can induce depressive-like behavior in rats and that pretreatment with nomifensine or imipramine can block the "depressogenic" effects of alcohol.
Pharmacology Biochemistry and Behavior  •  2011  |  View Paper
Neonatal exposure to nomifensine increased voluntary intake of 10% (v/v) alcohol when the rats were 2–3 months of age.
Journal of Neural Transmission  •  2005  |  View Paper
Treatment with nomifensine potentiated electrically or high potassium concentration-evoked [(3)H]dopamine release, but inhibited the effects of ethanol on [(3)H]dopamine release from the nucleus accumbens slices.
Alcohol  •  2002  |  View Paper
The potency of nomifensine as a reinforcer was significantly increased by 1000 mg/kg ethanol , but again, this enhancement was limited to the same two subjects.
Psychopharmacology  •  1997  |  View Paper
contrarily, NOM decreased the duration of ethanol narcosis, potentiated PCPA and antagonized the influence of AMPT.
Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia  •  1986  |  View Paper