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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Ethanol and Nitrazepam



Research Papers that Mention the Interaction

In combination with a noneffective oral dose (1 g/kg) of ethanol , the reductions in both total duration and peak frequency of RSA caused by nitrazepam , unlike those by Ro 41-3696 and zopiclone, were significantly potentiated.
Pharmacology  •  1994  |  View Paper
Brotizolam, nitrazepam and estazolam enhanced the sleeping time induced by ethanol and increased locomotor activity induced by methamphetamine, but did not affect the chewing behavior.
Arzneimittel-Forschung  •  1986  |  View Paper
When nitrazepam was used as the substrate (1 mM) for the isolated perfused rat liver, addition of ethanol (38 mM) led to an enhanced content of 7-amino derivative in the liver and in the perfusate, whereas the formation of 7-acetylamino derivative remained unchanged.
Drug metabolism and disposition: the biological fate of chemicals  •  1979  |  View Paper