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Last Updated: 3 years ago

Possible Interaction: Ethanol and Neuromuscular Depolarizing Agents

Research Papers that Mention the Interaction

We found that ethanol exposure potentiates the depolarizing action of GABA in GABAergic cortical interneurons of the embryonic mouse brain.
eLife  •  2019  |  View Paper
Ethanol also changed the shape of the spontaneous action potential in VTA neurons, reducing the amplitude of the spike after-hyperpolarization (in 74% of neurons) and also reducing the amplitude of the depolarizing phase of the action potential (in 86% of neurons tested).
Alcoholism, clinical and experimental research  •  1998  |  View Paper
The depolarizing agent potassium chloride (KG, 80 mm) produced less peak active tension in the fundus of ethanol‐fed rats (P < 0.01).
European journal of clinical investigation  •  1995  |  View Paper
Although there was no change in the total [Ca2+]i signal, ethanol (25-200 mM) dose-dependently inhibited the potentiation effects of depolarizing concentrations of K+ and BayK 8644 on the isoproterenol-stimulated cGMP, but not the cAMP, response.
Endocrinology  •  1992  |  View Paper
It has also been shown that ethanol potentiates the reversible, depolarizing effect of blue light on the transepithelial potential (TEP) of the isolated RPE.
Alcoholism, clinical and experimental research  •  1990  |  View Paper
It was concluded that ethanol modifies neurotransmission in the rat vas deferens preparation, by reducing the contractions produced by field stimulation and by depolarizing agents.
Acta physiologica Hungarica  •  1989  |  View Paper
In contrast, only higher ethanol concentrations (0.8 to 1.1%, w/v) blocked the increase in DA formation induced by high K + depolarizing concentrations (40 and 55 mM).
Biochemical pharmacology  •  1981  |  View Paper