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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Ethanol
drug:
Nefazodone
Research Papers that Mention the Interaction
“ Nefazodone may even promote ethanol drinking in a subset of patients.”
[Combination treatment with SSRI and cognitive behavior therapy for relapse prevention of alcohol-dependent men. Results of a randomized, controlled multicenter therapeutic study].“ Nefazodone might even increase the risk of consuming a larger amount of ethanol per relapse in a subset of patients.”
“While nefazodone failed to potentiate the sedative-hypnotic (depressant) effects of alcohol , imipramine tended to enhance them for psychomotor performance, memory assessments, and some subjective ratings.”
“One patient had a convulsion (cause not documented) after taking nefazodone 2000–3000 mg with methocarbamol and alcohol.”
“ Nefazodone caused a significant decrease in plasma corticosterone levels and EtOH consumption.”
Effects of nefazodone on voluntary ethanol consumption induced by isolation stress in young and aged rats“These results show that nefazodone modulates the mesolimbic dopamine system in a dopamine activity-dependent manner, and influences the neurochemical and behavioral effects of ethanol in the rat.”
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