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Last Updated: 3 years ago

Possible Interaction: Ethanol and Naloxone



Research Papers that Mention the Interaction

When ethanol tests were repeated in the presence of naloxone , at both lower and higher dose, ethanol inhibition on AVP secretion was only partial, with mean peak responses 2.5 times higher than basal values.
Journal of Neural Transmission  •  2009  |  View Paper
It has previously been reported that prior administration of naloxone may prevent the decrement in performance produced by alcohol.
Psychopharmacology  •  2004  |  View Paper
When naloxone was given after ethanol , the first injection reduced slightly but significantly ethanol-induced (1.5 g/kg) nystagmus, while the second injection did not enhance this counteraction any more.
Acta pharmacologica et toxicologica  •  1984  |  View Paper
Specifically, it was interesting to know the effect of naloxone , an agent known to block the development of dependence to opiates11, on the development of dependence on ethanol.
Nature  •  1977  |  View Paper
Patients who received greater than the standard dose of naloxone were 2.25 (95% CI, 1.83-2.77) times more likely to have been under the influence of alcohol when consuming the heroin that resulted in overdose.
Resuscitation  •  2005  |  View Paper
Opioid antagonists, like naloxone and naltrexone, decrease ethanol self-administration under a variety of conditions in different species of laboratory animals (e.g., rodents and nonhuman primates).
Alcoholism, clinical and experimental research  •  2001  |  View Paper
However, when ethanol was given together with naloxone , the peak rise induced by breast stimulation was only partially inhibited by ethanol (the mean PRL peak was 46.2% higher than baseline).
The PRL response to breast stimulation was not changed by the treatment with the lower (2 plus 10 mg) or the higher (4 plus 20 mg) dose of naloxone , whereas it was strikingly decreased by ethanol (mean peak was 25% higher than baseline).
Life sciences  •  1994  |  View Paper
However, when ethanol was given together with naloxone , the oxytocin rise induced by breast stimulation was only partially inhibited by ethanol (the mean oxytocin peak was 50% higher than baseline).
Acta endocrinologica  •  1992  |  View Paper
When ethanol was given together with naloxone , AVP rose by only two-fold in response to hypoglycemia.
Neuroendocrinology  •  1990  |  View Paper
The simultaneous infusion of naloxone (2 mg/hr over 90 min) and ethanol caused a rise in Cortisol, corticotrophin and prolactin whereas levels of growth hormone remained low.
Pharmacology Biochemistry and Behavior  •  1980  |  View Paper
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