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Last Updated: 2 years ago

Possible Interaction: Ethanol and Monoamine Oxidase Inhibitors

Research Papers that Mention the Interaction

Pretreatment of hepatocytes with N-acetyl cystein (ROS reducer), or dietary antioxidants (quercetin, reserveratrol), or NADPH (reduced nicotinamide adenine dinucleotide phosphate) oxidase inhibitor apocynin, significantly reduced ethanol (50 mM, 24 h) induced increases in ROS and H3AcK9.
Alcohol  •  2010  |  View Paper
The reversible MAO-A inhibitor, befloxatone (0.3-3 mg/kg), and the irreversible MAO-A inhibitor , clorgyline (10-30 mg/kg), also reduced ethanol self-administration.
Pharmacology Biochemistry and Behavior  •  1999  |  View Paper
In the presence of a potent type A MAO inhibitor (harmaline, 10 mg/kg maternal weight 2 hr before fetal delivery) co-treatment with ethanol was found to result in a 60% elevation of whole fetal brain norepinephrine levels.
General pharmacology  •  1988  |  View Paper
The turnover of cerebral 5-HT, determined from rates of increase in concentration of 5-HT or of decrease in concentration of 5-HIAA after the administration of a monoamine oxidase inhibiter , was modestly decreased during ethanol intoxication.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1970  |  View Paper